Department of Brain Sciences, Faculty of Medicine at Imperial College London.
Dr Michael Lattke’s overarching research interest is to understand how genomic programmes in their interaction with external signals control cellular functions in brain development and disease. He is particularly interested in "omics" approaches to systematically study programmes controlling the functions of astrocytes, a major glial cell type, which has diverse functions critical for brain development and homeostasis. Astrocyte dysfunction has been implicated in many neurological disorders, including neurodegenerative disorders such as Alzheimer's disease. Dr Lattke’s long-term vision is to harness these genomic mechanisms to restore or enhance protective astrocyte functions as therapeutic strategy for such disorders.